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Subsequently, divalent metal transporter 1 (DMT1) transports Fe + into the cytoplasm ( + ) can participate in the Fenton reaction, generating hydroxyl radicals (OH), which initiate and propagate lipid peroxidation chain reactions, thereby acting as one of the key triggers of ferroptosis ( + in ferritin, a cytosolic iron storage protein

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AAPS J (2017) 19(6):156475

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