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NNMT catalyzes the transfer of a methyl group from S-adenosyl-L-methionine to nicotinamide, influencing intracellular nicotinamide availability and interacting with NAD-associated metabolic processes

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Hence, recently it has been argued that plant immunity is better classified as extracellularly triggered immunity (ExTI) and intracellularly triggered immunity (ITI) (van der Burgh and Joosten, 2019)