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c-Myc, in turn, upregulates miR-181d and inhibits the expression of FBXL3 and CRY2, giving rise to a feed-forward loop [135]

et al., 2024) and zebrafish (Qian et al., 2025) suggesting a conserved disruption of dominant phyla across species in response to MPs exposure

J Clin Oncol 1992

Macrolide antibiotics such as troleandomycin, erythromycin, and erythromycin derivatives are metabolized, apparently by CYP3A, to metabolites that complex the cytochrome P450 heme iron and render it catalytically inactive