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Under stress and/or catabolic conditions such as cancer, sepsis/infections, post-surgery and trauma, the endogenous synthesis of glutamine does not appear to meet the human body demand, and hence glutamine assumes the role of a conditionally essential amino acid (Reference Liu, Ma and Luo6Reference Altman, Stine and Dang8)

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Metal and essential element concentrations during pregnancy and associations with autism spectrum disorder and attention-deficit/hyperactivity disorder in children

doi: 10.1007/s12272-010-1120-6

Among them, TLK117 results from de-esterification of TLK199 and is the most selective GSTP1-1 inhibitor (Fig