While taste alterations during treatment with GLP-1 receptor agonists or dual GIP/GLP-1 receptor agonists often improve over time as patients adjust to treatment, several strategies can help manage these changes and maintain adequate nutrition and quality of life
Vitamin K2 status and arterial stiffness among untreated migraine patients: a case-control study
This allows for a sufficient trial length and will allow for enough B12 to make a difference over a sustained period of time
How long does it take to go from a firm lump with good life quality to an infected mass with poor life quality

Some of the most common symptoms of piriformis injury are: Pain with sitting, standing, or lying longer than 15 to 20 minutes The pain improves with mobilization and worsens with no movement Pain when rising from a seated or squatting position Change of position does not relieve pain completely Difficulty walking or maintaining balance Foot numbness Headache Neck pain Abdominal, pelvic, and inguinal pain Pain with bowel movements Beyond these symptoms an individual can also watch out for signs such as the following: Tenderness over the piriformis muscle Palpable mass in the buttock Traction of affected limb provides moderate relief of pain Asymmetrical weakness in the affected limb Limited range of motion in the lower extremities Though signs and symptoms vary from person to person, if an individual is experiencing any of the above, there may be a deeper issue relating to the piriformis muscle which will require doctor intervention

Reassess your results at week 8 to determine if continuing is worthwhile