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Collectively, these potential clinical implications support further investigation and prioritization of this strategy in future translational and clinical trials

doi:10.1073/pnas.94.24.12786

3h), pointing towards increased mitochondrial biogenesis

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Free radicals increase because of various toxins, industrial chemicals, air pollutants, UV light, certain drugs, and pesticides.[xi] Free radicals in excess pair with other free electrons in cells resulting in decreased cellular function and disease