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Aging could be defined as a progressive decline of structural integrity and functional capacity of all organs and systems that weakens organism defenses and increases the vulnerability to diseases

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Cisplatin, as a common chemotherapeutic drug, can inhibit DNA replication and transcription in cancer cells through DNA cross-linking, leading to tumor cell growth arrest and apoptosis, however, tumor cells often develop clinical resistance to chemotherapeutic drugs, resulting in treatment failure (8)

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Fundamental & Clinical Pharmacology

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Quercetin modulates ferroptosis via the sirt1/nrf-2/ho-1 pathway and attenuates cartilage destruction in an osteoarthritis rat model

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The largest producers of beets today are the United States, Russia, and European nations such as France, Poland and Germany

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As expected, K47E, K91E, F112A, and H114E mutants showed various degrees of reduction in activation of c-MET (Fig

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