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Two histone deacetylase (HDAC) inhibitors, belinostat and reminostat, have been recently investigated in phase I/II clinical trials in HCC patients, which have shown potential efficacy of these targeted therapies [111]

Immunotherapy has been shown to be more effective in treating cancer, especially when combined with other treatments

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For example, a number of studies suggest that higher intake of selenium (and other antioxidants) offers protection against cognitive decline and conditions such as Alzheimers disease