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Overexpression of GSTs may contribute to increase detoxification of anticancer drugs 68

Interestingly, lean diabetics also exhibit larger adipocytes than healthy individuals, perhaps due to impaired differentiation of preadipocytes but not a result of different frequencies of stromal vascular cells, lipolysis, or levels of inflammatory mediators [35]

Since GPX1 has a certain reducing ability to hydroperoxides, it is classified as an oxidative stressase

The ability to maintain or restore optimal glutathione status represents a fundamental strategy for promoting healthspan and preventing oxidative stress-related pathological processes

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Reduced numbers of cerebellar Purkinje neurons have also been reported in patients with bipolar disorder [116]