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10.1093/intimm/dxx031 Int Immunol

Early metformin therapy (age 8-12 years) in girls with precocious pubarche to reduce hirsutism, androgen excess, and oligomenorrhea in adolescence

Bufkin et al

These oscillations in blood pressure involve a transition between hyper- and hypotension (corresponding to concentric and eccentric muscular contractions) within each repetition cycle (Perry and Lucas, 2021)

In other words, Low-GI foods and carbohydrate restriction are thus recommended as first-line interventions to manage PCOS and prevent associated long-term complications [80]

Nevertheless, additional research is required to clarify the mechanisms (511)