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doi: 10.3390/ijms22189664 54

In univariable logistic regression analysis, the risk of prolonged post-LTA hemodialysis was significantly higher in the high lactate group, compared to the low lactate group (OR: 5.34, 95%Cl: 1.01-28.4, p =0.049)

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This heterogeneity is partly genetic: mouse strains with polymorphisms in the Slc6a4 gene (encoding the 5-HT transporter) exhibit divergent responses to ethanol, with short-allele carriers showing heightened vulnerability to depression-like phenotypes

Taken together, these results demonstrate the multifaceted roles of VEGF-C and LECs in the tumor microenvironment