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Compound 44 exhibited the highest docking score with a binding energy of 10.36 kcal/mol and formed five crucial hydrogen bonds with Gly225, Phe113, and the NADPH cofactor as well as stable binding throughout the simulation (RMSD 0.250.35 nm)

Chronic fatigue is a symptom with identifiable drivers

Another well-known African medicinal plant, Sutherlandia frutescens (commonly known as cancer bush), is native to Southern Africa and contains flavonoids and triterpenoids that have demonstrated immune-boosting and anti-inflammatory effects [75]

Another critical mechanism of phytochemicals involves the direct scavenging of ROS and the inhibition of oxidative damage product formation

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