In general, there is the cytoprotection concept: the described effects of the stable gastric pentadecapeptide BPC 157 (that has been found to be safe in ulcerative colitis trials, phase II, without a lethal dose (LD1) in the toxicology studies) were ascribed to its particular cytoprotective capabilities and pleiotropic background as an acting cytoprotective peptide that protects cells and may cure muscle disturbances in particular [11,12,13,14,24,25]
M.de la ChapelleA.et al (2004)
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It explores how these peptides accelerate healing by promoting tissue regeneration, enhancing blood circulation, and reducing inflammation
As BCL-xL is uniquely upregulated in VCaP-AI, would co-targeting AR/ARv7 and BCL-xL elicit synergistic therapeutic efficacy in VCaP-AI subtype of CRPC