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Additionally, acteoside, a major active compound, has been reported to alleviate renal fibrosis and glycolipid metabolic disturbances by reducing oxidative stress and inflammation in -cells, modulating the unfolded protein response, improving mitochondrial dynamics, and enhancing -cell function and insulin secretion (69)

(H) Mean fluorescence intensity (MFI) of LIP in hepatocytes

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Importantly, this work also revealed impaired synaptic pruning and ASD-like behavioral phenotype in mice lacking neuronal autophagy

HPLC An HPLC Knauer system with a quaternary pump and a UV-DAD detector equipped with a Nucleodur C4 ec column (125 mm 4 mm, internal diameter 5 m, Macherey-Nagel), was used

Loose stools or diarrhea affect a smaller group and typically appear after the first week