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2HG inhibition in IDH-mutant AML patients impairs TET2 function that leads to loss of 5hmC and DNA hypermethylation (Lu et al., 2012

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C.KaplowitzN.Garcia-RuizC.ColellA.MirandaM.MariM.et al (1997)

BEISPIEL 30: Wirkung auf das pulmonale Hypertensionssyndrom Materialien und Methoden Die vorliegenden Experimente beschreiben die Wirkungen von Stickoxid(NO)-Agonisten und -Antagonisten und den Einfluss von NaBPC157 auf die Entwicklung des pulmonalen Hypertensionssyndroms (PHS) und von Gewebelsionen bei Hhnern