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2012;7(11):e49191

T cell activation by APCs induces symptoms similar to those in patients with IBD 37

The outcomes of this phase III clinical trial demonstrated significant superiority over those of the control group, leading to the approval of Cx601 (Alofisel) for the treatment of complex perianal fistulas in patients with Crohns disease, which received approval in March 2018 within the European Union and in October 2021 in Japan

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Moreover, electrophysiological tests revealed a larger amplitude and area of evoked muscle action potential (MAP) in the two groups that received 0.1 and 1 g/mL quercetin, respectively

International Journal of Molecular Sciences 2025, Vol 26, Page 8785 (2025) 26:8785