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In contrast, the use of PET imaging in a human study revealed that individuals carrying the ApoE4 gene variant show significantly higher levels of tau deposition, even when there are no A plaques present

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Thus, it can be concluded that both isolated microbes and peptides derived from kefir elicited an upregulation of anti-inflammatory cytokines and a concurrent downregulation of pro-inflammatory cytokine responses, signifying their potential as anti-inflammatory agents, as mentioned in Table 2 and Fig

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