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London, UK: Academic

[DOI] [PMC free article] [PubMed] [Google Scholar] 259.Luoqian J., Yang W., Ding X., Tuo Q.Z., Xiang Z., Zheng Z., Guo Y.J., Li L., Guan P., Ayton S., et al

In particular, RONS and inflammation mutually influence to give rise to a vicious cycle that drives synovial proliferation, angiogenesis, articular cartilage degradation and bone wreck in RA [17, 18]

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Among the limitations of our study, we acknowledge the relatively small sample size and the lack of control over other potential confounding factors, such as concurrent medications and the nutritional status of the patients