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10.1080/10717544.2025.2610532 31 KalinovK.GottschalkB.HirtlM.OstakuJ.GabrijeliS.SokolowskiA.et al (2025)

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As an example of recent progress, approximately 80% of all PubMed-indexed publications on lipedema have been published in the last decade, although many consist of case reports, small series, or hypothesis-driven reviews, with limited high-quality evidence

However, a significant limitation of the WHIMS trial was its use of progestin, a synthetic analogue of progesterone

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Additionally, a 1-year training study in 155 older women demonstrated that not only was a single day of high intensity RT (2 sets of 6-8 repetitions at 70%85% of 1RM) per week sufficient to improve memory at the cessation of the study compared to pre-training, but these cognitive benefits persisted for 1 year after training compared to balance-and-toning controls (Mcleod et al., 2024), but evidence does support that intensity mediates exercise-related neurogenesis and neuroplasticity in interval and aerobic exercise models (Marko et al., 2022