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The observation that thymic Treg development is restored in TAK1 and Carma-1 deficient mice crossed with transgenic mice expressing a constitutively active form of IKK (IKKEE-Tg) further reinforces the idea that NF-B signaling is sufficient to support Treg development (124128)

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see Additional file 8 for the GSEA enrichment plot and Additional file 1 for the fibroblast culture methods)

Molecular Formula: C35H48N10O15 Amino Acid Sequence: H-Trp-Ala-Gly-Gly-Asp-Ala-Ser-Gly-Glu-OH Molecular Weight: 848.8 g/mol View the HPLC Certificate here

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