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These disease models not only reveal the physiological and pathological mechanisms underlying organ cross-talk but also offer opportunities for developing targeted interventions to restore normal function

Dosage is commonly measured in micrograms (mcg) per day

Winter, G., Lobley, C

Similar to ERK1/2, p38 can affect the expression of some transcription factors, thus exerting regulatory effects (200)

46 , 48 , 49 Our findings showed a significant decrease in SOD and tGSH levels in the brain tissue of rats as a result of caffeine treatment, which is in agreement with a previous study demonstrating that decreased SOD and tGSH levels were associated with brain damage in the caffeine-induced epileptic seizure rat model