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This suggests that the study of the effect of metformin on NETs is an important area of research to broaden the understanding of the full clinical potential of metformin

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Macrophage activation and foam cell formation may explain the elevated CRP serum levels and contribute to disease progression (Figure 9)

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The redox state of thioredoxins and glutaredoxins was measured by covalent modification with the thiolreactive probe AMS (Molecular Probes) as described previously (Frand & Kaiser, 1999)

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& Molenaar, F

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Wang Z, Zhang Y, Ju E, Liu Z, Cao F, Chen Z, et al

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AMPK also modulates FA metabolism by reducing hydroxy methylglutaryl coenzyme A reductase (HCR) activity, a rate-limiting enzyme for cholesterol synthesis, via phosphorylation and degrading FOXO1 in ECs upon LS stimuli [218]

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