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Schisandrins elimination half-life (t 1/2 ) in females was 2-fold longer, while maximal plasma concentration (C max ) was 10-fold higher than in males (62)

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The maximum induction of these enzymes occurred at 1224 h after high temperature stress, which was preceded by the initial increase of H 2 O 2 content

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Of the affected pathways, glutathione has been suggested to be a primer for T-cell metabolism for inflammation [69] while T-cell activation has shown to be dependent on extracellular alanine [70]