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Backwash A process in which flow is reversed through a filter to remove accumulated solids, biofilm, and debris, restoring filtration performance

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Thus, microbial changes in PD indicate a shift from a symbiotic, neuroprotective microbiota to a pro-inflammatory, neurotoxic microbial composition, which can promote peripheral immune activation, gut barrier failure, and, eventually, neuroinflammation and dopaminergic neuronal death [44]

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