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doi: 10.1146/annurev-immunol-042718-041841 15 BuS.ChengX.ChenM.YuY

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It has been proposed that NOX1-induced O2 at the colons luminal surface Influence various processes such as bacterial virulence, expression of bacteriostatic proteins, epithelial renewal, restitution, and microbiota composition to control the intestinal innate immune defense and homeostasis (109)