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Following injection, AdV particles target innate immune cells like DCs and macrophages and stimulate innate immune responses by engaging multiple pattern-recognition receptors including those that bind dsDNA in particular TLR9 to induce type I interferon secretion 8

Acknowledgements This work was supported by funding to DJT by BASF Beauty Care Solutions, France

In the control, dpp was solely expressed in either the dpp-Gal4 or the nub-Gal4 region, and there was no cell death in the pouch region except in the notum region (Fig