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Brahm H, Piehl-Aulin K, Saltin B, Ljunghall S

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For patients without an underlying absorption disorder who received injections for general wellness, stopping should produce no noticeable negative effects, especially if dietary B12 intake is adequate

[18] Systemic side effects may include headache, irritability, restlessness, depression, fatigue, or edema resulting from fluid retention

This may result from the combination of compounds, variations in pH, or preservatives used in the mixture

We also demonstrated that DPI significantly increases mitochondrial ROS production in MNA cells, but not in non-MNA cells, indicating a MYCN-dependent effect (16)