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doi: 10.1182/blood-2004-10-4094 17 FrascaLFedeleGDeaglioSCapuanoCPalazzoRVaisittiTet al

The STEP UP trial, a Phase 3b study published in The Lancet Diabetes & Endocrinology in 2025, evaluated a 7.2 mg weekly injection dose in over 1,400 adults with obesity (BMI of 30 or higher) and without diabetes