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Furthermore, the subsequent red blood cell lysis products release various toxic substances and lead to the death of neurons, ultimately leading to secondary brain injury ( in vivo and in vitro by regulating GPX4 and ACSL4 (Qu et al., 2021)

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On the other hand, VEGF-VEGFR2 could increase vascular permeability by activating VEGFR2TSAdSrc-cadherin and PI3KAkteNOSNO signaling pathways (Fig

The theory is that lower doses might provide anti-inflammatory benefit with fewer gastrointestinal side effects

Behav Brain Res (2016) 730:6370.10.1016/j.bbr.2016.10.037 13 TardivoVCrobedduEPilloniGFontanellaMSpenaGPancianiPPet alSay no to spinal cord injury: is nitric oxide an option for therapeutic strategies