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Handle these only by the sides

Moreover, chronic alcohol consumption can lead to alterations in serotonin receptor expression and function

P4 plays a pivotal role in triggering polyploidization and the differentiation of the elongated fibroblastic stromal cells into rounded secreting decidual cells, thereby initiating the secretion of stromal factors such as prolactin (PRL) and insulin-like growth factor binding protein 1 (IGFBP1) to establish an immunotolerant and nutrient-rich environment essential for successful embryo implantation and pregnancy maintenance [4, 5]

TR: Writing original draft

466 The CBS regulatory domain can serve as a novel curative target, while SAM and its structural analogs can serve as original scaffolds for new drugs