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The goal is to tailor support in a way that makes sense for the individual

Retrieved 21 April 2020

Avoid excessive simple carbohydrates, which continually spike insulin and actively turn off AMPKthe exact pathway MOTS-c is trying to turn on

NICE guidelines recommend evidence-based weight management through dietary modification (600 kcal/day deficit), 150300 minutes weekly moderate-intensity physical activity, and behavioural change strategies