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Practitioners who work with AOD-9604 do so under research-use frameworks, and the evidence base for efficacy, while mechanistically interesting, did not survive the Phase IIb primary endpoint test

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Risks and Side Effects While generally safe, vitamin B12 injections can have side effects or risks, such as: Mild pain, swelling, or redness at the injection site Dizziness, headache, or nausea Allergic reactions (rare) Hypokalemia (low potassium levels) in individuals with severe deficiency undergoing treatment People with allergies to cobalt or who have Lebers disease should avoid B12 injections unless specifically advised by a doctor