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Lancet 395 , 10541062 (2020)

Taken together, the peptide-liposome-ROS triggering drug complex that incorporated with maleimide we designed provides a ROS drug enhancement and targeted delivery platform, representing a potential solution for AML therapy

The difference between them in injury target and pathological process stems from the essential difference of organ metabolic function

The net result of conjugation with active metabolites is detoxification of these reactive chemical species

J Inorg Bioch 197:110698

Patient-centred strategies must identify patients tumour, current and planned conventional therapies (chemotherapy, endocrine therapy, targeted therapy and immunotherapy), comorbidities, organ function, nutrition profile, dietary habits and existing medication or supplement use since these factors critically impact both the efficacy and safety of supplementary approaches (236)