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Cell-type specific CpGs were identified as described before [7, 8], and most of these were hypermethylated in HSPCs

B.NuxollA

Zhang J, Liu H, Yan H, Huang G, Wang B (2013) Null genotypes of GSTM1 and GSTT1 contribute to increased risk of diabetes mellitus: a meta-analysis

Specific formulations and bioactive compounds regulate pathways including PI3K/Akt, Nrf2/HO-1, and VEGF, contributing to better glycemic control and reduced complications such as diabetic retinopathy, cardiomyopathy, osteoporosis, and peripheral neuropathy

Studies have shown that oxidative stress and microvascular changes induced by diabetes can damage the integrity of the BTB in diabetic patients, leading to the infiltration of harmful substances into the seminiferous tubules, thereby affecting spermatogenesis [268]