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Description

253 In senescent cells, mitochondrial proton leak was observed, associated with the weakened proton gradient and further reducing the efficiency of ATP synthesis

full brightening usually takes 6 to 10 sessions

23,25 It is beyond the scope of this overview to cover this topic in detail herein, but coverage is provided in other reviews

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Cell Mol Life Sci 74(21):38633881 Toader AM, Hoteiuc O, Bidian C, Oltean DD, Tabaran F, Grad O, Clichici S, Mitrea DR (2021) Neuronal apoptosis can be prevented by the combined therapy with melatonin and hypothermia in a neonatal rat model of hypoxic-ischemic encephalopathy