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However, in addition to neurotoxicity associated with A peptide and pTau, other key determinants of the neurodegenerative process need to be included in the list of the main causative factors of AD

doi: 10.1038/s41409-018-0221-6 42 NegrinRS

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Aging is associated with structural and functional changes in the mitochondria (Seo et al., 2016), which is accompanied by the alterations of biophysical properties of the membrane including alteration in the electron transport chain complex activities, decreased fluidity, and energy imbalance and mitochondrial failure (Tan et al., 2018)

In addition, the levels of GC biomarkers, including CEA and CA19-9, were also decreased in the serum of the OP-B group compared with the control group (Fig

Blood levels of glutathione increased after one month at both dosages, although the increase was more at the higher dose