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Description

Sci Data 5 , 180004 (2018)

To further support the impact of CBS on replenishing GSH levels under cystine-restricted conditions, we expressed a codon-optimized CBS (CBS OPT ), which is resistant to the designed sgRNA (Fig

1G), and by the end of the experiment AL- and CR-fed 3xTg males had comparable levels of fat mass, lean mass, and adiposity, while DL-fed 3xTg males had reduced fat mass and adiposity relative to both AL and CR-fed 3xTg males (Fig