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Food, specifically the amount of fish and shellfish that men eat, and renal function all affect TMAO levels

In addition, vitamin D induces autophagy, and reduces apoptosis, ultimately resulting in the survival of pancreatic -cells

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This review consolidates the core mechanisms through which microbiota-derived metabolites including short-chain fatty acids, bile acids, branched-chain amino acids, trimethylamine N-oxide, tryptophan derivatives, succinate, polyamines etc., regulate IMF deposition and proposes a targeted intervention framework, the gut microbiota/metabolites-IMF axis

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