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374,375,376 Bacteroides dorei BDX-01 downregulates the expression of NLRP3, ASC and Caspase-1 in colon tissues and reduces the secretion of IL-1 by regulating bile acid metabolism pathways

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on Day 28: DEXILANT 63% vs placebo 40%)

SIRT1 can directly bind to transcription factors, including PGC-1, and regulate their activity 18

doi: 10.3390/metabo11020083 72 LenisY

A random number generator was used to determine Placebo or NAC first and the participant was given the other treatment at their subsequent encounter