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The complex gene interaction network in Figure 4B illustrates the common pathways through which polyphenolic compounds like Myricetin, Luteolin, Kaempferol, Caffeic Acid, Quercetin, Apigenin, Curcumin, and Ferulic Acid exert their therapeutic effects against Alzheimer's disease (AD)

The liver safety issues with the Pfizer compounds were related to their specific chemical structures rather than being a class effect of all small-molecule GLP-1 agonists

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Pellets were resuspended in a volume equivalent to 10% of the initial culture volume with PBS containing 1% Triton X-100 and transferred into tubes containing glass beads (MP Biomedicals)