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This condition often leads to cell death and/or the necrotic lysis of sensitive cells, resulting in the microvascular and alveolar injury typical of pulmonary oxygen toxicity [22, 37, 146]

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76 A study on the effect of genome-wide cardiac DNA methylation on overall gene expression in myocardial samples from patients with end-stage chronic Chagas disease cardiomyopathy (CCC) showed that two differentially expressed methylated genes, KCNA4 and KCNIP4, were involved in the regulation of potassium channels