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The samples were then centrifuged at 1,800 g for 15 min to separate serum and investigate proinflammatory cytokines (IL-6, IL-1 , and TNF- ) and inflammatory cytokines (COX2)

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In terms of next steps, the company will meet with the FDA to discuss the future development of VK2735

on the other hand, ERS induces apoptosis through the activation of three up-stream signaling proteins: inositol requiring protein-1, activating transcription factor-6 and protein kinase RNA (PKR)-like ER kinase