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The accumulation of excessive ROS due to hazardous chemicals, carcinogens, and mutagenic substances in tobacco can damage mitochondrial DNA, inducing oxidative stress

[DOI] [PMC free article] [PubMed] [Google Scholar] 359.Shelar S

Development of polysorbate 80/phospholipid mixed micellar formation for docetaxel and assessment of its in vivo distribution in animal models

Handle using appropriate laboratory safety procedures

EMBO J 20(23):65916600

These changes together promote pathological phenotypes such as uncontrolled proliferation, tissue invasion, and therapeutic resistance across a wide range of chronic diseases (Wang G