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While the previously mentioned review and studies report beneficial effects, other rigorously controlled trials have found no significant changes in VOmax after Ashwagandha supplementation [57, 132]

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Should we worry about algae being contaminated

Store reconstituted vials refrigerated at 2-8 degrees Celsius, and most sources report stability for 30-60 days once reconstituted, provided you avoid repeated freeze-thaw cycles

Pre-existing conditions (cardiovascular disease, autoimmune disorders) introduce unpredictable responses

For instance, SLC22A is highly expressed in astrocytic projections within various neuronal regions such as hippocampus, nigrostriatal axis and hypothalamus loci and is a competent transporter for the neurotransmitters like epinephrine, norepinephrine and histamine