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65 A recent study on naturally aged mice found that in the absence of an additional trigger, the activation of cyclic GMPAMP synthase (cGAS)stimulator of interferon genes (STING) signaling pathway is sufficient to promote aging-related inflammation and neurodegeneration by triggering reactive microglial transcriptional states

ATP-Binding Cassette Transporter G1 (ABCG1) (40) ABCG1 is expressed in many different cell types and mediates the efflux of cholesterol from the cell to HDL particles

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During active ulcerative colitis, IL-1, one of the most prominent mediators of colon inflammation, is secreted in greater quantities 36

See the diagram below