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Mendt MK, Rezvani E, Shpall

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Abstract Liver diseases, including hepatocellular carcinoma (HCC), non-alcoholic fatty liver disease (NAFLD), and alcoholic liver disease (ALD), impose a significant global health burden, with over 2 million deaths annually and substantial economic losses

One lead material showed effective siRNA delivery in a MDA-MB-231-Luc xenograft mouse tumor model

polynucleotide shuffling & interrupted synthesis) and non-stochastic polynucleotide reassembly to recombine at least two forms of a nucleic acid which is capable of conferring upon a genetic vector the ability to replicate autonomously in mammalian cells