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Their in vivo experiments showed that 9cRA (delivered via the intracerebroventricular route) also antagonized the immunoreactivity of T-helper cells and locomotor activity in the striatum of rats indirectly through a signaling mechanism involving bone morphogenetic protein

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Expert Rev Cardiovasc Ther

Liu, W.-J

Capsules or tablets for oral administration may contain a controlled-release formulation as may be provided in a dispersion of active compound in hydroxypropyl methylcellulose or related material known to alter the kinetics of release of the active agent

Carnitine and acylcarnitine can also be used as metabolic messengers to participate in the communication between tissues and coordinate energy metabolism between tissues