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Recent analyses in gastrointestinal stromal tumors (GIST) further illustrate how nanoscale platforms can integrate targeted delivery with tumor microenvironment modulation and explicit translational design principles to address persistent therapeutic limitations, reinforcing that many of the engineering logics discussed here generalize across GI oncology rather than being confined to gastric cancer alone (163165)

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E.MaL.KuhlowA.PabelU.PomplunD.TeubnerW.MeinlW.2001Human cytosolic sulphotransferases: genetics, characteristics, toxicological aspects.4821-2, (October 2001),2740,0027-5107 38

Azoospermia, the absence of spermatozoa in ejaculates, can be classified into obstructive and non-obstructive NOA forms

Activation of the receptor of the second messenger IP3 leads to the storage of Ca 2+ entry (SOCE) in the ER membrane, and the influx of Ca 2+ signal transduction activates the TF NFAT (122, 123)