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Valproic acid induces apoptosis in mitochondria and death receptors, and its anti-lung cancer effects can be enhanced by inhibiting cyclin-dependent kinases [81]

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In turn, changes in TJ proteins lead to an increase in the paracellular permeability of the epithelial barrier ( 3.2 The role of gut microbiota in biosynthesis and degradation of mucous layer components The mucous layer separates gut microorganisms from the epithelium

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[2] Long-term follow-up: Once stable on maintenance therapy, routine blood monitoring is not usually necessary unless new symptoms develop