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Following the identification of oxidative stress-related genes (HMOX1, DNAJB1, GADD45B), higher expression levels were observed in HepG2 ATP7B-KO cells compared to HepG2 cells

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The initial dose of HM30-tesirine maintained tumour volumes close to their pre-treatment size 8 days post-treatment (78 31 mm 3 ), whereas control and cisplatin-treated tumours had reached 518 130 mm 3 and 199 72 mm 3 , respectively by this time ( n = 36 mice